Roughly a day after launch, the Crew-8 mission is expected to dock with the International Space Station with four new crew members.

Aboard will be NASA astronauts Matthew Dominick, Michael Barratt, Jeanette Epps and Russian cosmonaut Alexander Grebenkin. They are set to replace the outgoing Crew-7 mission, which includes NASA astronaut Jasmin Moghbeli, European Space Agency astronaut Andreas Mogensen, Japanese astronaut Satoshi Furukawa and Russian cosmonaut Konstantin Borisov, who arrived at the ISS in August 2023.